A ketogenic diet extends longevity and healthspan in adult mice

Calorie restriction, without malnutrition, has been shown to increase lifespan and is associated with a shift away from glycolysis toward beta-oxidation. The objective of this study was to mimic this metabolic shift using low-carbohydrate diets and to determine the influence of these diets on longev...

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Pubblicato in:Cell Metab
Autori principali: Roberts, Megan N., Wallace, Marita A., Tomilov, Alexey A., Zhou, Zeyu, Marcotte, George R., Tran, Dianna, Perez, Gabriella, Gutierrez-Casado, Elena, Koike, Shinchiro, Knotts, Trina A., Imai, Denise M., Griffey, Stephen M., Kim, Kyoungmi, Hagopian, Kevork, Haj, Fawaz G., Baar, Keith, Cortopassi, Gino A., Ramsey, Jon J., Lopez-Dominguez, Jose Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609489/
https://ncbi.nlm.nih.gov/pubmed/28877457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.08.005
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