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Photochemical Generation of Benzyl Cations That Selectively Cross-Link Guanine and Cytosine in DNA
UV irradiation of several aryl boronates efficiently produced bifunctional benzyl cations that selectively form guanine-cytosine cross-links in DNA. Photoinduced homolysis of the C–Br bond took place with the aryl boronate bromides 3a and 4a, generating free radicals that were oxidized to benzyl cat...
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| Published in: | Org Lett |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5609456/ https://ncbi.nlm.nih.gov/pubmed/27191599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00755 |
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