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Photo-Switchable DNA Interstrand Cross-Link Formation by a Coumarin-Modified Nucleotide()
A coumarin-modified pyrimidine nucleoside (1) has been synthesized using Cu(I)-catalyzed click reaction and incorporated into oligodeoxynucleotides (ODNs). Interstrand cross-links are produced upon irradiation of ODN containing 1 at 350 nm. Cross-linking occurs via [2+2] cycloaddition reaction with...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151308/ https://ncbi.nlm.nih.gov/pubmed/24840115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310609 |
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