Enhancer-mediated oncogenic function of the menin tumor suppressor in breast cancer

While the multiple endocrine neoplasia type 1 (MEN1) gene functions as a tumor suppressor in a variety of cancer types, we explored its oncogenic role in breast tumorigenesis. The MEN1 gene product menin is involved in H3K4 trimethylation and co-activates transcription. We integrated ChIP-seq and RN...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Dreijerink, Koen M.A., Groner, Anna C., Vos, Erica S.M., Font-Tello, Alba, Gu, Lei, Chi, David, Reyes, Jaime, Cook, Jennifer, Lim, Elgene, Lin, Charles Y., de Laat, Wouter, Rao, Prakash, Long, Henry, Brown, Myles
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609449/
https://ncbi.nlm.nih.gov/pubmed/28273452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.025
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