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Direct Binding of DNA by Tumor Suppressor Menin

Menin is a tumor suppressor that is mutated in patients with multiple endocrine neoplasia type I (MEN1), an inherited tumor-prone syndrome. Since there is no obvious conserved structural domain in menin that suggests a function, little is known as to how menin suppresses tumorigenisis. Although meni...

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Detalhes bibliográficos
Main Authors: La, Ping, Silva, Albert C., Hou, Zhaoyuan, Wang, Haoren, Schnepp, Robert W., Yan, Nieng, Shi, Yigong, Hua, Xianxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858586/
https://ncbi.nlm.nih.gov/pubmed/15331604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M409358200
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