PD-L1 is an activation-independent marker of brown adipocytes

Programmed death ligand 1 (PD-L1) is expressed on a number of immune and cancer cells, where it can downregulate antitumor immune responses. Its expression has been linked to metabolic changes in these cells. Here we develop a radiolabeled camelid single-domain antibody (anti-PD-L1 VHH) to track PD-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Ingram, Jessica R., Dougan, Michael, Rashidian, Mohammad, Knoll, Marko, Keliher, Edmund J., Garrett, Sarah, Garforth, Scott, Blomberg, Olga S., Espinosa, Camilo, Bhan, Atul, Almo, Steven C., Weissleder, Ralph, Lodish, Harvey, Dougan, Stephanie K., Ploegh, Hidde L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608754/
https://ncbi.nlm.nih.gov/pubmed/28935898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00799-8
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