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Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

The monogenic and monoallelic expression of only one out of >1000 mouse olfactory receptor (ORs) genes requires the formation of large heterochromatic chromatin domains that sequester the OR gene clusters. Within these domains, intergenic transcriptional enhancers evade heterochromatic silencing...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Monahan, Kevin, Schieren, Ira, Cheung, Jonah, Mumbey-Wafula, Alice, Monuki, Edwin S, Lomvardas, Stavros
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608512/
https://ncbi.nlm.nih.gov/pubmed/28933695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28620
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