Enhancer interaction networks as a means for singular olfactory receptor expression

The transcriptional activation of one out of ~2800 olfactory receptor (OR) alleles is a poorly understood process. Here, we identify a plethora of putative OR enhancers and study their in vivo activity in olfactory neurons. Distinguished by an unusual epigenetic signature, candidate OR enhancers are...

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Udgivet i:Cell
Main Authors: Markenscoff-Papadimitriou, Eirene, Allen, William E., Colquitt, Bradley M., Goh, Tracie, Murphy, Karl K., Monahan, Kevin, Mosley, Colleen P., Ahituv, Nadav, Lomvardas, Stavros
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243057/
https://ncbi.nlm.nih.gov/pubmed/25417106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.033
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