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An epigenetic trap stabilizes singular olfactory receptor expression

The molecular mechanisms regulating olfactory receptor (OR) expression in the mammalian nose are not yet understood. Here, we identify the transient expression of histone demethylase LSD1, and the OR-dependent expression of Adenylyl Cyclase 3 (Adcy3) as requirements for initiation and stabilization...

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書誌詳細
主要な著者: Lyons, David B., Allen, William E., Goh, Tracie, Tsai, Lulu, Barnea, Gilad, Lomvardas, Stavros
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929589/
https://ncbi.nlm.nih.gov/pubmed/23870122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.06.039
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