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Integrating genomic information and signaling dynamics for efficient cancer therapy

The field of cancer systems biology has made great strides in understanding oncogenic pathway signaling and enumerating mutations involved in oncogenesis. However, application of these datasets to patient stratification, and to the design of personalized therapy, is in its infancy. We review BRAF an...

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Veröffentlicht in:Curr Opin Syst Biol
Hauptverfasser: Stewart-Ornstein, Jacob, Lahav, Galit
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608455/
https://ncbi.nlm.nih.gov/pubmed/28944311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2016.12.013
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