Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest

RATIONALE: Post-ischemic changes in cellular metabolism alter myocardial and neurological function. Pyruvate dehydrogenase (PDH), the limiting step in mitochondrial glucose oxidation, is inhibited by increased expression of PDH kinase (PDK) during ischemia/reperfusion injury. This results in decreas...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Piao, Lin, Fang, Yong-Hu, Kubler, Manfred M., Donnino, Michael W., Sharp, Willard W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608301/
https://ncbi.nlm.nih.gov/pubmed/28934276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185046
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker