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Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions
Moloney murine leukemia (MLV) virus-based retroviral vectors integrate predominantly in acetylated enhancers and promoters. For this reason, mLV integration sites can be used as functional markers of active regulatory elements. Here, we present a retroviral scanning tool, which allows the genome-wid...
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| Опубликовано в: : | J Vis Exp |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MyJove Corporation
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608156/ https://ncbi.nlm.nih.gov/pubmed/28605390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55919 |
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