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PKA activity exacerbates hypoxia-induced ROS formation and hypoxic injury in PC-12 cells
Hypoxia is a primary factor in many pathological conditions. Hypoxic cell death is commonly attributed to metabolic failure and oxidative injury. cAMP-dependent protein kinase A (PKA) is activated in hypoxia and regulates multiple enzymes of the mitochondrial electron transport chain, thus may be im...
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| Publicado no: | Toxicol Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608019/ https://ncbi.nlm.nih.gov/pubmed/28751209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2017.07.895 |
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