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Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins

Over the past decade, channelrhodopsins became indispensable in neuroscientific research where they are used as tools to non-invasively manipulate electrical processes in target cells. In this context, ion selectivity of a channelrhodopsin is of particular importance. This article describes the inve...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Grimm, Christiane, Vierock, Johannes, Hegemann, Peter, Wietek, Jonas
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608014/
https://ncbi.nlm.nih.gov/pubmed/28570519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55497
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