17β-Estradiol Dysregulates Innate Immune Responses to Pseudomonas aeruginosa Respiratory Infection and Is Modulated by Estrogen Receptor Antagonism

Females have a more severe clinical course than males in terms of several inflammatory lung conditions. Notably, females with cystic fibrosis (CF) suffer worse outcomes, particularly in the setting of Pseudomonas aeruginosa infection. Sex hormones have been implicated in experimental and clinical st...

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Vydáno v:Infect Immun
Hlavní autoři: Abid, Shadaan, Xie, ShangKui, Bose, Moumita, Shaul, Philip W., Terada, Lance S., Brody, Steven L., Thomas, Philip J., Katzenellenbogen, John A., Kim, Sung Hoon, Greenberg, David E., Jain, Raksha
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607430/
https://ncbi.nlm.nih.gov/pubmed/28784925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00422-17
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