17β-Estradiol Dysregulates Innate Immune Responses to Pseudomonas aeruginosa Respiratory Infection and Is Modulated by Estrogen Receptor Antagonism

Females have a more severe clinical course than males in terms of several inflammatory lung conditions. Notably, females with cystic fibrosis (CF) suffer worse outcomes, particularly in the setting of Pseudomonas aeruginosa infection. Sex hormones have been implicated in experimental and clinical st...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Abid, Shadaan, Xie, ShangKui, Bose, Moumita, Shaul, Philip W., Terada, Lance S., Brody, Steven L., Thomas, Philip J., Katzenellenbogen, John A., Kim, Sung Hoon, Greenberg, David E., Jain, Raksha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607430/
https://ncbi.nlm.nih.gov/pubmed/28784925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00422-17
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