17β-Estradiol Dysregulates Innate Immune Responses to Pseudomonas aeruginosa Respiratory Infection and Is Modulated by Estrogen Receptor Antagonism

Females have a more severe clinical course than males in terms of several inflammatory lung conditions. Notably, females with cystic fibrosis (CF) suffer worse outcomes, particularly in the setting of Pseudomonas aeruginosa infection. Sex hormones have been implicated in experimental and clinical st...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Abid, Shadaan, Xie, ShangKui, Bose, Moumita, Shaul, Philip W., Terada, Lance S., Brody, Steven L., Thomas, Philip J., Katzenellenbogen, John A., Kim, Sung Hoon, Greenberg, David E., Jain, Raksha
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607430/
https://ncbi.nlm.nih.gov/pubmed/28784925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00422-17
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