17β-Estradiol Dysregulates Innate Immune Responses to Pseudomonas aeruginosa Respiratory Infection and Is Modulated by Estrogen Receptor Antagonism

Females have a more severe clinical course than males in terms of several inflammatory lung conditions. Notably, females with cystic fibrosis (CF) suffer worse outcomes, particularly in the setting of Pseudomonas aeruginosa infection. Sex hormones have been implicated in experimental and clinical st...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Abid, Shadaan, Xie, ShangKui, Bose, Moumita, Shaul, Philip W., Terada, Lance S., Brody, Steven L., Thomas, Philip J., Katzenellenbogen, John A., Kim, Sung Hoon, Greenberg, David E., Jain, Raksha
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Host Response and Inflammation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607430/
https://ncbi.nlm.nih.gov/pubmed/28784925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00422-17
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