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Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human Erythrocytes

Plasmodium falciparum, the parasite that causes the deadliest form of malaria, has evolved multiple proteins known as invasion ligands that bind to specific erythrocyte receptors to facilitate invasion of human erythrocytes. The EBA-175/glycophorin A (GPA) and Rh5/basigin ligand-receptor interaction...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Dankwa, Selasi, Chaand, Mudit, Kanjee, Usheer, Jiang, Rays H. Y., Nobre, Luis V., Goldberg, Jonathan M., Bei, Amy K., Moechtar, Mischka A., Grüring, Christof, Ahouidi, Ambroise D., Ndiaye, Daouda, Dieye, Tandakha N., Mboup, Souleymane, Weekes, Michael P., Duraisingh, Manoj T.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607420/
https://ncbi.nlm.nih.gov/pubmed/28760933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00074-17
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