Inhibitory Humoral Responses to the Plasmodium falciparum Vaccine Candidate EBA-175 Are Independent of the Erythrocyte Invasion Pathway

Plasmodium falciparum utilizes multiple ligand-receptor interactions for invasion. The invasion ligand EBA-175 is being developed as a major blood-stage vaccine candidate. EBA-175 mediates parasite invasion of host erythrocytes in a sialic acid-dependent manner through its binding to the erythrocyte...

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Autori principali: Badiane, Aida S., Bei, Amy K., Ahouidi, Ambroise D., Patel, Saurabh D., Salinas, Nichole, Ndiaye, Daouda, Sarr, Ousmane, Ndir, Omar, Tolia, Niraj H., Mboup, Souleymane, Duraisingh, Manoj T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Clinical Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754519/
https://ncbi.nlm.nih.gov/pubmed/23761656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00135-13
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