Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human Erythrocytes

Plasmodium falciparum, the parasite that causes the deadliest form of malaria, has evolved multiple proteins known as invasion ligands that bind to specific erythrocyte receptors to facilitate invasion of human erythrocytes. The EBA-175/glycophorin A (GPA) and Rh5/basigin ligand-receptor interaction...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Dankwa, Selasi, Chaand, Mudit, Kanjee, Usheer, Jiang, Rays H. Y., Nobre, Luis V., Goldberg, Jonathan M., Bei, Amy K., Moechtar, Mischka A., Grüring, Christof, Ahouidi, Ambroise D., Ndiaye, Daouda, Dieye, Tandakha N., Mboup, Souleymane, Weekes, Michael P., Duraisingh, Manoj T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607420/
https://ncbi.nlm.nih.gov/pubmed/28760933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00074-17
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