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Bacteroides fragilis Enterotoxin Induces Formation of Autophagosomes in Endothelial Cells but Interferes with Fusion with Lysosomes for Complete Autophagic Flux through a Mitogen-Activated Protein Kinase-, AP-1-, and C/EBP Homologous Protein-Dependent Pathway

Bacteroides fragilis enterotoxin (BFT), a virulence factor of enterotoxigenic B. fragilis (ETBF), plays an essential role in mucosal inflammation. Although autophagy contributes to the pathogenesis of diverse infectious diseases, little is known about autophagy in ETBF infection. This study was cond...

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Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Ko, Su Hyuk, Jeon, Jong Ik, Myung, Hyun Soo, Kim, Young-Jeon, Kim, Jung Mogg
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607419/
https://ncbi.nlm.nih.gov/pubmed/28694294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00420-17
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