Bacteroides fragilis Enterotoxin Induces Formation of Autophagosomes in Endothelial Cells but Interferes with Fusion with Lysosomes for Complete Autophagic Flux through a Mitogen-Activated Protein Kinase-, AP-1-, and C/EBP Homologous Protein-Dependent Pathway

Bacteroides fragilis enterotoxin (BFT), a virulence factor of enterotoxigenic B. fragilis (ETBF), plays an essential role in mucosal inflammation. Although autophagy contributes to the pathogenesis of diverse infectious diseases, little is known about autophagy in ETBF infection. This study was cond...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Ko, Su Hyuk, Jeon, Jong Ik, Myung, Hyun Soo, Kim, Young-Jeon, Kim, Jung Mogg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607419/
https://ncbi.nlm.nih.gov/pubmed/28694294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00420-17
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