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Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinase- and NF-κB-Dependent Pathway, Leading to Modulation of Apoptosis

The Bacteroides fragilis enterotoxin (BFT), a virulence factor of enterotoxigenic B. fragilis (ETBF), interacts with intestinal epithelial cells and can provoke signals that induce mucosal inflammation. Although expression of heme oxygenase-1 (HO-1) is associated with regulation of inflammatory resp...

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Vydáno v:Infect Immun
Hlavní autoři: Ko, Su Hyuk, Rho, Da Jeong, Jeon, Jong Ik, Kim, Young-Jeon, Woo, Hyun Ae, Lee, Yun Kyung, Kim, Jung Mogg
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995915/
https://ncbi.nlm.nih.gov/pubmed/27324483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00191-16
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