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Crude Preparations of Helicobacter pylori Outer Membrane Vesicles Induce Upregulation of Heme Oxygenase-1 via Activating Akt-Nrf2 and mTOR–IκB Kinase–NF-κB Pathways in Dendritic Cells

Helicobacter pylori sheds outer membrane vesicles (OMVs) that contain many surface elements of bacteria. Dendritic cells (DCs) play a major role in directing the nature of adaptive immune responses against H. pylori, and heme oxygenase-1 (HO-1) has been implicated in regulating function of DCs. In a...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Ko, Su Hyuk, Rho, Da Jeong, Jeon, Jong Ik, Kim, Young-Jeon, Woo, Hyun Ae, Kim, Nayoung, Kim, Jung Mogg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962631/
https://ncbi.nlm.nih.gov/pubmed/27185786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00190-16
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