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Identification and correction of spatial bias are essential for obtaining quality data in high-throughput screening technologies

Spatial bias continues to be a major challenge in high-throughput screening technologies. Its successful detection and elimination are critical for identifying the most promising drug candidates. Here, we examine experimental small molecule assays from the popular ChemBank database and show that scr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mazoure, Bogdan, Nadon, Robert, Makarenkov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607347/
https://ncbi.nlm.nih.gov/pubmed/28931934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11940-4
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