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Identification and correction of spatial bias are essential for obtaining quality data in high-throughput screening technologies

Spatial bias continues to be a major challenge in high-throughput screening technologies. Its successful detection and elimination are critical for identifying the most promising drug candidates. Here, we examine experimental small molecule assays from the popular ChemBank database and show that scr...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Mazoure, Bogdan, Nadon, Robert, Makarenkov, Vladimir
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607347/
https://ncbi.nlm.nih.gov/pubmed/28931934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11940-4
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