Plant flavones enhance antimicrobial activity of respiratory epithelial cell secretions against Pseudomonas aeruginosa

Flavones are a class of natural plant secondary metabolites that have anti-inflammatory and anti-bacterial effects. Some flavones also activate the T2R14 bitter taste receptor, which is expressed in motile cilia of the sinonasal epithelium and activates innate immune nitric oxide (NO) production. Fl...

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Bibliographic Details
Published in:PLoS One
Main Authors: Hariri, Benjamin M., McMahon, Derek B., Chen, Bei, Adappa, Nithin D., Palmer, James N., Kennedy, David W., Lee, Robert J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607194/
https://ncbi.nlm.nih.gov/pubmed/28931063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185203
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