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PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa

Airway submucosal gland serous cells are important sites of fluid secretion in conducting airways. Serous cells also express the cystic fibrosis (CF) transmembrane conductance regulator (CFTR). Protease-activated receptor 2 (PAR-2) is a G protein-coupled receptor that activates secretion from intact...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: McMahon, Derek B., Carey, Ryan M., Kohanski, Michael A., Adappa, Nithin D., Palmer, James N., Lee, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174824/
https://ncbi.nlm.nih.gov/pubmed/33655758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00411.2020
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