PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa

Airway submucosal gland serous cells are important sites of fluid secretion in conducting airways. Serous cells also express the cystic fibrosis (CF) transmembrane conductance regulator (CFTR). Protease-activated receptor 2 (PAR-2) is a G protein-coupled receptor that activates secretion from intact...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: McMahon, Derek B., Carey, Ryan M., Kohanski, Michael A., Adappa, Nithin D., Palmer, James N., Lee, Robert J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174824/
https://ncbi.nlm.nih.gov/pubmed/33655758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00411.2020
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