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PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa

Airway submucosal gland serous cells are important sites of fluid secretion in conducting airways. Serous cells also express the cystic fibrosis (CF) transmembrane conductance regulator (CFTR). Protease-activated receptor 2 (PAR-2) is a G protein-coupled receptor that activates secretion from intact...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: McMahon, Derek B., Carey, Ryan M., Kohanski, Michael A., Adappa, Nithin D., Palmer, James N., Lee, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174824/
https://ncbi.nlm.nih.gov/pubmed/33655758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00411.2020
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