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Microphysiological Systems to Assess Nonclinical Toxicity
The liver and the kidney are key toxicity target organs during drug development campaigns as they typically carry the burden of drug transport and metabolism. Primary hepatocytes and proximal tubule epithelial cells grown in traditional in vitro 2-D culture systems do not maintain transporter and me...
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| Publicado no: | Curr Protoc Toxicol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607027/ https://ncbi.nlm.nih.gov/pubmed/28777442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.27 |
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