MicroCT-based phenomics in the zebrafish skeleton reveals virtues of deep phenotyping in a distributed organ system

Phenomics, which ideally involves in-depth phenotyping at the whole-organism scale, may enhance our functional understanding of genetic variation. Here, we demonstrate methods to profile hundreds of phenotypic measures comprised of morphological and densitometric traits at a large number of sites wi...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hur, Matthew, Gistelinck, Charlotte A, Huber, Philippe, Lee, Jane, Thompson, Marjorie H, Monstad-Rios, Adrian T, Watson, Claire J, McMenamin, Sarah K, Willaert, Andy, Parichy, David M, Coucke, Paul, Kwon, Ronald Y
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Computational and Systems Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606849/
https://ncbi.nlm.nih.gov/pubmed/28884682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26014
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