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Dwarfism and Increased Adiposity in the gh1 Mutant Zebrafish vizzini

Somatic growth and adipogenesis are closely associated with the development of obesity in humans. In this study, we identify a zebrafish mutant, vizzini, that exhibits both a severe defect in somatic growth and increased accumulation of adipose tissue. Positional cloning of vizzini revealed a premat...

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Detalhes bibliográficos
Main Authors: McMenamin, Sarah K., Minchin, James E.N., Gordon, Tiffany N., Rawls, John F., Parichy, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602633/
https://ncbi.nlm.nih.gov/pubmed/23456361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1734
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