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Phenomics-based quantification of CRISPR-induced mosaicism in zebrafish
Genetic mosaicism can manifest as spatially variable phenotypes that vary from site-to-site within an organism. Here, we use imaging-based phenomics to quantitate phenotypes at many sites within the axial skeleton of CRISPR-edited G0 zebrafish. Through characterization of loss-of-function cell clust...
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| Pubblicato in: | Cell Syst |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7213258/ https://ncbi.nlm.nih.gov/pubmed/32191876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.02.007 |
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