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Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm
Homologous Recombination (HR) repair is essential for repairing DNA double strand breaks (DSB) in dividing cells and preventing tumorigenesis. BRCA2 plays an important role in HR by recruiting the DNA recombinase RAD51 to the DSB. Despite being a popular model organism in genetic and cancer research...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705637/ https://ncbi.nlm.nih.gov/pubmed/29184099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16725-3 |
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