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Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm
Homologous Recombination (HR) repair is essential for repairing DNA double strand breaks (DSB) in dividing cells and preventing tumorigenesis. BRCA2 plays an important role in HR by recruiting the DNA recombinase RAD51 to the DSB. Despite being a popular model organism in genetic and cancer research...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705637/ https://ncbi.nlm.nih.gov/pubmed/29184099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16725-3 |
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