Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa

BACKGROUND: Retinitis pigmentosa (RP) is the most common inherited retinal degenerative disease yet with no effective treatment available. The sigma-1 receptor (S1R), a ligand-regulated chaperone, emerges as a potential retina-protective therapeutic target. In particular, pharmacological activation...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Yang, Huan, Fu, Yingmei, Liu, Xinying, Shahi, Pawan K., Mavlyutov, Timur A., Li, Jun, Yao, Annie, Guo, Steven Z.-W., Pattnaik, Bikash R., Guo, Lian-Wang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606113/
https://ncbi.nlm.nih.gov/pubmed/28927431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0202-z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker