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SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models
Single-cell sequencing enables the inference of tumor phylogenies that provide insights on intra-tumor heterogeneity and evolutionary trajectories. Recently introduced methods perform this task under the infinite-sites assumption, violations of which, due to chromosomal deletions and loss of heteroz...
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| Pubblicato in: | Genome Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5606061/ https://ncbi.nlm.nih.gov/pubmed/28927434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1311-2 |
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