Targeting Cancer Cells with a Bisphosphonate Prodrug

Nitrogen-containing bisphosphonates have anti-tumor activity in certain breast cancer and myeloma patients. However, these drugs have limited oral absorption, tumor cell entry and activity, and cause bone side effects. The potencies of phosphorylated antiviral drugs have been increased by administer...

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Опубликовано в: :ChemMedChem
Главные авторы: Matsumoto, Kenji, Hayashi, Kosuke, Murata-Hirai, Kaoru, Iwasaki, Masashi, Okamura, Haruki, Minato, Nagahiro, Morita, Craig T., Tanaka, Yoshimasa
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605902/
https://ncbi.nlm.nih.gov/pubmed/27786425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600465
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