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Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid

Exposing human tumor cells to nitrogen‐containing bisphosphonates, such as zoledronic acid (Zol), greatly increases their susceptibility to killing by γδ T cells. Based on this finding and other studies, cancer immunotherapy using γδ T cells and nitrogen‐containing bisphosphonates has been studied i...

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Detalhes bibliográficos
Main Authors: Idrees, Atif S. M., Sugie, Tomoharu, Inoue, Chiyomi, Murata‐Hirai, Kaoru, Okamura, Haruki, Morita, Craig T., Minato, Nagahiro, Toi, Masakazu, Tanaka, Yoshimasa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755363/
https://ncbi.nlm.nih.gov/pubmed/23387443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12124
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