Targeting Cancer Cells with a Bisphosphonate Prodrug

Nitrogen-containing bisphosphonates have anti-tumor activity in certain breast cancer and myeloma patients. However, these drugs have limited oral absorption, tumor cell entry and activity, and cause bone side effects. The potencies of phosphorylated antiviral drugs have been increased by administer...

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Pubblicato in:ChemMedChem
Autori principali: Matsumoto, Kenji, Hayashi, Kosuke, Murata-Hirai, Kaoru, Iwasaki, Masashi, Okamura, Haruki, Minato, Nagahiro, Morita, Craig T., Tanaka, Yoshimasa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605902/
https://ncbi.nlm.nih.gov/pubmed/27786425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600465
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