Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis

Spatiotemporal balancing of cellular proliferation and differentiation is crucial for postnatal tissue homoeostasis and organogenesis. During embryonic development, pancreatic progenitors simultaneously proliferate and differentiate into the endocrine, ductal and acinar lineages. Using in vivo clona...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Larsen, Hjalte List, Martín-Coll, Laura, Nielsen, Alexander Valentin, Wright, Christopher V. E., Trusina, Ala, Kim, Yung Hae, Grapin-Botton, Anne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605525/
https://ncbi.nlm.nih.gov/pubmed/28928395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00258-4
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