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Cell Cycle–Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

Organogenesis relies on the spatiotemporal balancing of differentiation and proliferation driven by an expanding pool of progenitor cells. In the mouse pancreas, lineage tracing at the population level has shown that the expanding pancreas progenitors can initially give rise to all endocrine, ductal...

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Dettagli Bibliografici
Pubblicato in:PLoS Biol
Autori principali: Kim, Yung Hae, Larsen, Hjalte List, Rué, Pau, Lemaire, Laurence A., Ferrer, Jorge, Grapin-Botton, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364879/
https://ncbi.nlm.nih.gov/pubmed/25786211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002111
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