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Cell Cycle–Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

Organogenesis relies on the spatiotemporal balancing of differentiation and proliferation driven by an expanding pool of progenitor cells. In the mouse pancreas, lineage tracing at the population level has shown that the expanding pancreas progenitors can initially give rise to all endocrine, ductal...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Kim, Yung Hae, Larsen, Hjalte List, Rué, Pau, Lemaire, Laurence A., Ferrer, Jorge, Grapin-Botton, Anne
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364879/
https://ncbi.nlm.nih.gov/pubmed/25786211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002111
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