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Cell Cycle–Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

Organogenesis relies on the spatiotemporal balancing of differentiation and proliferation driven by an expanding pool of progenitor cells. In the mouse pancreas, lineage tracing at the population level has shown that the expanding pancreas progenitors can initially give rise to all endocrine, ductal...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Kim, Yung Hae, Larsen, Hjalte List, Rué, Pau, Lemaire, Laurence A., Ferrer, Jorge, Grapin-Botton, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364879/
https://ncbi.nlm.nih.gov/pubmed/25786211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002111
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