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REST represses a subset of the pancreatic endocrine differentiation program

To contribute to devise successful beta-cell differentiation strategies for the cure of Type 1 diabetes we sought to uncover barriers that restrict endocrine fate acquisition by studying the role of the transcriptional repressor REST in the developing pancreas. Rest expression is prevented in neuron...

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Publicat a:Dev Biol
Autors principals: Martin, David, Kim, Yung-Hae, Sever, Dror, Mao, Chai-An, Haefiiger, Jacques-Antoine, Grapin-Botton, Anne
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732702/
https://ncbi.nlm.nih.gov/pubmed/26156633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.07.002
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