RHINOVIRUS INFECTION OF ORMDL3 TRANSGENIC MICE IS ASSOCIATED WITH REDUCED RHINOVIRUS VIRAL LOAD AND AIRWAY INFLAMMATION

Oroscomucoid 3 (ORMDL3), a gene localized to chromosome 17q21, has been linked in epidemiologic studies to childhood asthma and rhinoviral (RV) infections. As the single nucleotide polymorphisms linking ORMDL3 to asthma is associated with increased expression of ORMDL3, we have utilized hORMDL3(zp3-...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Song, Dae Jin, Miller, Marina, Beppu, Andrew, Rosenthal, Peter, Das, Sudipta, Karta, Maya, Vuong, Christine, Mehta, Amit Kumar, Croft, Michael, Broide, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605463/
https://ncbi.nlm.nih.gov/pubmed/28827284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601412
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