RHINOVIRUS INFECTION OF ORMDL3 TRANSGENIC MICE IS ASSOCIATED WITH REDUCED RHINOVIRUS VIRAL LOAD AND AIRWAY INFLAMMATION

Oroscomucoid 3 (ORMDL3), a gene localized to chromosome 17q21, has been linked in epidemiologic studies to childhood asthma and rhinoviral (RV) infections. As the single nucleotide polymorphisms linking ORMDL3 to asthma is associated with increased expression of ORMDL3, we have utilized hORMDL3(zp3-...

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Publicat a:J Immunol
Autors principals: Song, Dae Jin, Miller, Marina, Beppu, Andrew, Rosenthal, Peter, Das, Sudipta, Karta, Maya, Vuong, Christine, Mehta, Amit Kumar, Croft, Michael, Broide, David H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605463/
https://ncbi.nlm.nih.gov/pubmed/28827284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601412
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