FSTL1 PROMOTES ASTHMATIC AIRWAY REMODELING BY INDUCING ONCOSTATIN M

Chronic asthma is associated with airway remodeling and decline in lung function. Here we show that follistatin like 1 (Fstl1), a mediator not previously associated with asthma is highly expressed by macrophages in the lungs of severe human asthmatics. Chronic allergen challenged Lys-Cre(tg)/Fstl1(Δ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Miller, Marina, Beppu, Andrew, Rosenthal, Peter, Pham, Alexa, Das, Sudipta, Karta, Maya, Song, Dae Jin, Vuong, Christine, Doherty, Taylor, Croft, Michael, Zuraw, Bruce, Zhang, Xu, Gao, Xiang, Aceves, Seema, Chouiali, Fazila, Hamid, Qutayba, Broide, David H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811198/
https://ncbi.nlm.nih.gov/pubmed/26355153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501105
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