ADAM10-mediated ICOSL Shedding on B cells is Necessary for Proper T cell ICOS Regulation and T(FH) Responses

The proper regulation of inducible costimulator (ICOS) and its ligand (ICOSL) have been shown to be essential for maintaining proper immune homeostasis. Loss of either protein results in defective humoral immunity, and overexpression of ICOS results in aberrant antibody production resembling lupus....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Lownik, Joseph C, Luker, Andrea J., Damle, Sheela R., Cooley, Lauren Folgosa, El Sayed, Riham, Hutloff, Andreas, Pitzalis, Costantino, Martin, Rebecca K., El Shikh, Mohey Eldin M, Conrad, Daniel H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605448/
https://ncbi.nlm.nih.gov/pubmed/28814605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700833
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker