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Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns

The elimination of infected or tumor cells by direct lysis is a key T and NK cell effector function. T and NK cells can kill target cells by coordinated secretion of cytotoxic granules containing one or both pore-forming proteins, perforin and granulysin and combinations of granzyme (Gzm) family eff...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Bengsch, Bertram, Ohtani, Takuya, Herati, Ramin Sedaghat, Bovenschen, Niels, Chang, Kyong-Mi, Wherry, E. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605401/
https://ncbi.nlm.nih.gov/pubmed/28322863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2017.03.009
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