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Therapies targeting DNA and RNA in Huntington's disease

No disease-slowing treatments exist for Huntington’s disease (HD), but its monogenic inheritance makes it an appealing candidate for the development of therapeutics targeting pathogenic processes close to its root genetic cause. HD is caused by CAG repeat expansions in the HTT gene, which encodes hu...

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Dades bibliogràfiques
Publicat a:Lancet Neurol
Autors principals: Wild, Edward J, Tabrizi, Sarah
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604739/
https://ncbi.nlm.nih.gov/pubmed/28920889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(17)30280-6
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