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Therapies targeting DNA and RNA in Huntington's disease
No disease-slowing treatments exist for Huntington’s disease (HD), but its monogenic inheritance makes it an appealing candidate for the development of therapeutics targeting pathogenic processes close to its root genetic cause. HD is caused by CAG repeat expansions in the HTT gene, which encodes hu...
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| Publicado no: | Lancet Neurol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5604739/ https://ncbi.nlm.nih.gov/pubmed/28920889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(17)30280-6 |
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