Sitagliptin, a dipeptidyl peptidase-4 inhibitor, suppresses CXCL5 and SDF-1 and does not accelerate intestinal neoplasia formation in Apc(Min/+) mice fed a high-fat diet

The relationship between type 2 diabetes mellitus and intestinal neoplasia has been shown epidemiologically. A high-fat diet (HFD) is also known to promote insulin resistance, which is a risk factor for intestinal neoplasia. Dipeptidyl peptidase-4 (DPP-4) inhibitors are used in the clinic for the tr...

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Bibliografske podrobnosti
izdano v:Oncol Lett
Main Authors: Fujiwara, Kaori, Inoue, Takuya, Henmi, Yujiro, Hirata, Yoshimasa, Naka, Yutaka, Hara, Azusa, Kakimoto, Kazuki, Nouda, Sadaharu, Okada, Toshihiko, Kawakami, Ken, Takeuchi, Toshihisa, Higuchi, Kazuhide
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604155/
https://ncbi.nlm.nih.gov/pubmed/28943949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6698
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