Nature of action of Sitagliptin, the dipeptidyl peptidase-IV inhibitor in diabetic animals

OBJECTIVE: The aim of this study was to evaluate the dipeptidyl peptidase-IV (DPP-IV) inhibitor sitagliptin with respect to mode of inhibition and its in vivo duration of inhibition and efficacy in type 2 diabetes animal model. MATERIALS AND METHODS: DPP-IV enzyme assay was carried out in human plas...

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Bibliographic Details
Main Authors: Davis, Joseph A., Singh, Shuchita, Sethi, Sachin, Roy, Subhasis, Mittra, Shivani, Rayasam, Geetavani, Bansal, Vinay, Sattigeri, Jitendra, Ray, Abhijit
Format: Artigo
Language:Inglês
Published: Medknow Publications 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941613/
https://ncbi.nlm.nih.gov/pubmed/20927248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.68425
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