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Transmembrane Helices Are an Overlooked Source of Major Histocompatibility Complex Class I Epitopes

About a fourth of the human proteome is anchored by transmembrane helices (TMHs) to lipid membranes. TMHs require multiple hydrophobic residues for spanning membranes, and this shows a striking resemblance with the requirements for peptide binding to major histocompatibility complex (MHC) class I. I...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Bianchi, Frans, Textor, Johannes, van den Bogaart, Geert
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604083/
https://ncbi.nlm.nih.gov/pubmed/28959259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01118
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