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Transmembrane Helices Are an Overlooked Source of Major Histocompatibility Complex Class I Epitopes
About a fourth of the human proteome is anchored by transmembrane helices (TMHs) to lipid membranes. TMHs require multiple hydrophobic residues for spanning membranes, and this shows a striking resemblance with the requirements for peptide binding to major histocompatibility complex (MHC) class I. I...
Enregistré dans:
| Publié dans: | Front Immunol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5604083/ https://ncbi.nlm.nih.gov/pubmed/28959259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01118 |
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